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“Better than nothing.” That’s one infectious disease expert’s assessment of Sinovac Biotech’s COVID-19 vaccine, following reports that hundreds of Indonesian health care workers who had received the vaccine caught the disease anyway.  At least 10 doctors have died after getting both doses of Sinovac’s CoronaVac vaccine, according to the Indonesian Medical Association. It’s unclear how widespread these “breakthrough” infections are. It’s also not clear how severe most of the infections are. Little peer-reviewed data on the vaccine are available. What information is available suggests that the vaccine is less potent than others, especially against the highly contagious delta variant that was first detected in India.  However, access to more effective vaccines is limited in much of the world, experts note. Indonesia is one of dozens of countries where the Chinese company’s vaccine makes up a substantial part of the available doses.  While the shortage of published peer-reviewed data makes it hard to evaluate the vaccine, a few available studies provide a glimpse.  The government of Uruguay FILE – Empty vials to be filled with the Pfizer/BioNTech vaccine are seen at a production facility in Reinbek, near Hamburg, Germany, April 30, 2021.Pfizer-BioNTech
The Pfizer-BioNTech shot performed better against infections in general in the study, lowering rates by 78%. But hospitalizations and deaths were about the same.  It’s not clear what the dominant variant was during the study, however.  A key measure of vaccine potency is the level of neutralizing antibodies — the proteins the immune system produces that prevent the virus from infecting cells.  The Pfizer and Moderna vaccines produce very high levels of these antibodies, which help maintain protection against variants, said Peter Hotez, dean of the National School of Tropical Medicine and a professor at the Baylor College of Medicine. “Yes, you’re getting some breakthrough infections with the delta variant, but they tend not to be serious infections,” he said. “People aren’t being hospitalized or losing their lives because of COVID-19.” “When you look at some of the data on the Sinovac vaccine,” he added, “the levels of virus-neutralizing antibody, even after two doses, can still be quite low.” The Sinovac vaccine produced lower levels of these antibodies than seven other vaccines, including those from Pfizer, Moderna, University of Oxford-AstraZeneca and Johnson & Johnson, according to a study in the journal Nature Medicine.The antibody response is even less effective against the delta variant, which has exploded in Indonesia and many parts of the world.  It’s not clear, however, exactly what that decline means for patients. The vaccine still offers protection against the most serious forms of the disease, a Chinese official told state media. Sorry, but your browser cannot support embedded video of this type, you can
download this video to view it offline.Download File360p | 4 MB480p | 5 MB540p | 7 MB720p | 13 MB1080p | 22 MBOriginal | 263 MB Embed” />Copy Download AudioIn China’s first delta outbreak, in Guangdong province earlier this month, “none of those vaccinated infections became severe cases, and none of the severe cases were vaccinated,” said Feng Zijian, former deputy director at the Chinese Center for Disease Control and Prevention.  Meanwhile, supplies of other vaccines are arriving slowly in much of the world.   “Sometimes, that’s all people have access to,” Hotez said. “It’s better than nothing.” 
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U.S. President Joe Biden is holding talks Wednesday with a group of governors from eight Western states about wildfire preparedness as much of the region deals with drought. Biden and other administration officials will be speaking from the White House with the governors joining by video. White House press secretary Jen Psaki told reporters last week the meeting will “focus on how the federal government can improve wildfire preparedness and response efforts, protect public safety, and deliver assistance to our people in times of urgent need.” Those attending include Democratic governors Gavin Newsom of California, Jared Polis of Colorado, Michelle Lujan Grisham of New Mexico, Steve Sisolak of Nevada, Kate Brown of Oregon and Jay Inslee of Washington, along with Republican governors Spencer Cox of Utah and Mark Gordon of Wyoming. Not among the group are three other Republican governors from the region: Doug Ducey of Arizona, Brad Little of Idaho and Greg Gianforte of Montana. Gianforte tweeted Friday that he was “disappointed to learn in news stories” that the president “didn’t offer a seat at the table to Montana and other states facing a severe wildfire season.” The National Interagency Fire Center, which coordinates the mobilization of resources to battle wildfires in the United States, has warned that many Western states are facing a greater than usual likelihood that significant wildfires will occur in the next few months. The U.S. Drought Monitor reports wide areas of Arizona, California, New Mexico, Nevada and Utah are experiencing extreme or exceptional drought. 
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Cities in the Pacific Northwest of North America reported power outages Tuesday, both from failures of utility companies and rolling blackouts due to heavy power demand. Seattle and Portland temperatures were expected to fall Tuesday, below Monday’s record highs, but inland, the city of Spokane, Washington, continued to record high temperatures and experience rolling blackouts in the city. Lytton, British Columbia, set Canada’s all-time high temperature Sunday with 46.6 degrees Celsius, only to see it broken less than 24 hours later, hitting 47.9 C Monday. Officials said Tuesday that several deaths in Portland and Seattle were tied to the extreme heat. In Vancouver, British Columbia, first responders have said that as many as two dozen deaths may be attributed to the high temperatures. On Tuesday, the U.N. World Meteorological Organization called the heat wave hitting the Pacific Northwest corner of the United States “exceptional and dangerous” and says it could last at least another five days.Guests at Sunriver resort near Bend, Oregon line up to get into the pool on June 29, 2021 as temperatures were predicted to hit 106 degrees Fahrenheit.Speaking to reporters from Geneva, a WMO spokeswoman said while records have fallen in the U.S. states of Oregon and Washington, western Canada has seen extreme heat as well. The official said the temperatures for this time of year and location are shocking. “It’s in the province of British Columbia, it’s to the Rocky Mountains, the Glacier National Park, and yet we’re seeing temperatures which are more typical of the Middle East or North Africa.” In an area used to temperatures 20 to 30 degrees cooler, the WMO said, the extreme heat poses major health threats to residents as well as agriculture and the environment. The WMO said the extreme heat is caused by “an atmospheric blocking pattern,” which has led to a “heat dome” — a large area of high pressure trapped by low pressure on either side. The organization said the temperatures would likely peak early this week on the coast and by the middle of the week in the interior of British Columbia. Afterward, the baking heat is expected to move east toward Alberta. On its Twitter account late Monday, the U.S. National Weather Service in Portland, Oregon, reported cooler air was already in the region along the coastline. In a tweet Sunday, the Oregon Climate Service said that the climate system is no longer in a balanced state, and that such heat events “are becoming more frequent and intense, a trend projected to continue.” This report includes information from The Associated Press.
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